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  • Rosalía Agustí, María Eugenia Giorgi, Verónica M. Mendoza, Carola Gallo-Rodriguez, Rosa M de Lederkremer
  • Chemistry, Medicine
  • Bioorganic & medicinal chemistry
  • 2007 (First Publication: 1 April 2007)
  • The mucin-like glycoproteins of Trypanosoma cruzi have novel O-linked oligosaccharides that are acceptors of sialic acid in the trans-sialidase (TcTS) reaction. The transference of sialic acid fromContinue Reading
  • Rosalía Agustí, Gastón París, Laura Ratier, Alberto Carlos C Frasch, Rosa M de Lederkremer
  • Biology, Medicine
  • Glycobiology
  • 2004 (First Publication: 14 April 2004)
  • Chagas' disease, caused by Trypanosoma cruzi, affects about 18 million people in Latin America, and no effective treatment is available to date. To acquire sialic acid from the host glycoconjugates,Continue Reading
  • Rosalía Agustí, Alicia S Couto, Oscar Campetella, Alberto Carlos C Frasch, Rosa M de Lederkremer
  • Biology, Medicine
  • Molecular and biochemical parasitology
  • 1998 (First Publication: 1 November 1998)
  • Both, culture-derived and metacyclic trypomastigotes of Trypanosoma cruzi shed a glycoprotein, the shed acute phase antigen, that is responsible for the trans-sialidase activity. In the present workContinue Reading