Rosa Caballero-Santos

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OBJECTIVES: Inflammatory mediators appear to play key role in the development of adult respiratory distress syndrome (ARDS) in critically ill patients. Cytokines involved in the early phase include tumor necrosis factor alpha (TNFa) and selected interleukins. Experimental infusion of TNFa has been shown to cause ARDS and increased concentration of cytokines(More)
BACKGROUND We hypothesized that implanting cells in a chondral defect at a density more similar to that of the intact cartilage could induce them to synthesize matrix with the features more similar to that of the uninjured one. METHODS We compared the implantation of different doses of chondrocytes: 1 million (n = 5), 5 million (n = 5), or 5 million(More)
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