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This book gives a detailed yet readable account of the design, implementation, testing, and analysis of a spoken task-oriented dialogue system. Although there is a thorough reporting of related work, the plural in the main title is a bit misleading, as the book focuses on only one system, built by the authors at Duke University. The subtitle is well(More)
This paper presents information about the dialog structure of actual human-computer dialog obtained from the analysis of 141 dialogs collected during experimental interaction with a variable initiative spoken natural language dialog system organized around the paradigm of the Missing Axiom Theory for language use. The reported results indicate there are(More)
In this study, we assessed the underlying mechanisms by which proteinases released from activated neutrophils mediate fibronectin degradation. Purified human neutrophils (1 x 10(6)) were incubated for 1 hr with 1 microM PMA in the absence or presence of different proteinase inhibitors in 96-well microtiter plates that were coated with 125I-labeled(More)
Factors contributing to protection against experimental tuberculosis have been studied with refined and well characterized fractions from mycobacteria and with certain unrelated antigens. Mice were vaccinated intravenously with various combinations of materials presented on minute oil droplets in saline emulsions and were later challenged by aerosol. The(More)
The number of people with dementia of the Alzheimer's type (DAT) continues to grow. One of the significant impacts of this disease is a decline in the ability to communicate using natural language. This decline in language facility often results in decreased social interaction and life satisfaction for persons with DAT and their caregivers. One possible(More)
A pragmatic architecture for voice dialog machines aimed at the equipment repair problem has been implemented. This architecture exhibits a number of behaviors required for efficient human-machine dialog. These behaviors include: (1) (2) (3) (4) (5) problem solving to achieve a target goal the ability to carry out subdialogs to achieve appropriate subgoals(More)
A pragmatic architecture for voice dialog machines aimed at the equipment repair problem has been implemented which exhibits a number of behaviors required for eecient human-machine dialog. These behaviors include: (1) problem solving to achieve a target goal, (2) the ability to carry out subdialogs to achieve appropriate subgoals and to pass control(More)
This paper presents an analysis of the dialogue structure of actual human-computer interactions. The 141 dialogues analyzed were produced from experiments with a variable initiative spoken natural language dialogue system organized around the paradigm of the Missing Axiom Theory for language use. Results about utterance classification into subdialogues,(More)
An architecture for voice dialogue machines is described with emphasis on the problem solving and high level decision making mechanisms. The architecture provides facilities for generating voice interactions aimed at cooperative human-machine problem solving. It assumes that the dialogue will consist of a series of local self-consistent subdialogues each(More)
'Orphan' zoonotic diseases attract disproportionately low scientific and public health attention for the impact that they can have. This article pulls together information on their health burden in the UK from routine and enhanced data sources. These diseases are heterogeneous in nature; some have very low case numbers (e.g. hydatid disease), whilst others(More)