Rongting Xu

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Receptor protein tyrosine phosphatase α (RPTPα)-mediated Src activation is required for survival of tested human colon and oestrogen receptor-negative breast cancer cell lines. To explore whether mutated RPTPα participates in human carcinogenesis, we sequenced RPTPα cDNAs from five types of human tumours and found splice mutants in ∼30% of colon, breast,(More)
In our previous study, an intronic MAR sequence in human PI3Kγ gene (PIMAR) was identified using bioinformatics and biochemical methods. We used MatInspector® software to identify potential binding sites for MAR-binding proteins in PIMAR. In this study, a tissue-specific MAR-binding protein (SATB1) was used to characterize the potential binding sites.(More)
  • Hong Du, Qianjin Feng, +7 authors Xin Niu
  • Drug development and industrial pharmacy
  • 2014
CONTEXT The difference between the chemical polarities of the two categories of active chemical constituents in Chinese angelica volatile oil (CAVO) and Chinese angelica water extract (CAWE) greatly limit the development and clinical application of Chinese angelica preparation. OBJECT The aim of this study is to design and prepare a "whole Chinese(More)
The authors are quite imprecise in their statement "Yet Src tyrosine phosphorylation was greatly reduced (implying activation)" this phrase must be associated with the particular C-terminal pTyr site which is a negative regulator of Src activity. Similar statements are made throughout the manuscript; the phosphorylation status should be associated to a(More)
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