Rongmin Su

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  • Weijun Fang, Yijun Cai, +7 authors Shoufa Han
  • Bioorganic & medicinal chemistry letters
  • 2009
Topical microbicides offer women the opportunity to protect themselves from sexual HIV transmission under their own control. A series of poly[styrene-alt-(maleic anhydride)] derivatives were prepared by amidation or hydrolysis of the anhydride moiety. The derivatives were shown to be of low cell toxicity and effectively inhibited HIV-1 infections in an in(More)
Micellar mannose nanoparticles were constructed from poly{styrene-co-[(maleic anhydride)-alt-styrene]} with fluorophores or quenchers doped into the hydrophobic inner cores, allowing the direct monitoring of multivalent lectin-glycan interactions. The mannose-displaying nanoparticles bind Con A and sperm surface lectins with high affinity, suggesting their(More)
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