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- Adam J. Bass, Vesteinn Thorsson, +252 authors Jia Xiang Liu
- Nature
- 2014
Gastric cancer is a leading cause of cancer deaths, but analysis of its molecular and clinical characteristics has been complicated by histological and aetiological heterogeneity. Here we describe a… (More)
- Matthew Bott, Marie Brevet, +15 authors Marc Ladanyi
- Nature Genetics
- 2011
Malignant pleural mesotheliomas (MPMs) often show CDKN2A and NF2 inactivation, but other highly recurrent mutations have not been described. To identify additional driver genes, we used an integrated… (More)
- Xiaoju Wang, Jianjun Yu, +12 authors Arul M. Chinnaiyan
- The New England journal of medicine
- 2005
BACKGROUND
New biomarkers, such as autoantibody signatures, may improve the early detection of prostate cancer.
METHODS
With a phage-display library derived from prostate-cancer tissue, we… (More)
- Daniel J. Brat, Roel G. W. Verhaak, +304 authors Jianan Zhang
- The New England journal of medicine
- 2015
BACKGROUND
Diffuse low-grade and intermediate-grade gliomas (which together make up the lower-grade gliomas, World Health Organization grades II and III) have highly variable clinical behavior that… (More)
- Lucia Regales, Yixuan Gong, +10 authors William Pao
- The Journal of clinical investigation
- 2009
EGFR is a major anticancer drug target in human epithelial tumors. One effective class of agents is the tyrosine kinase inhibitors (TKIs), such as gefitinib and erlotinib. These drugs induce dramatic… (More)
- S H Kwak, Ronglai Shen, John Schiefelbein
- Science
- 2005
The position-dependent specification of root epidermal cells in Arabidopsis provides an elegant paradigm for cell patterning during development. Here, we describe a new gene, SCRAMBLED (SCM),… (More)
- Rajal B Shah, Rohit Mehra, +10 authors Kenneth J. Pienta
- Cancer research
- 2004
Understanding the biology of prostate cancer metastasis has been limited by the lack of tissue for study. We studied the clinical data, distribution of prostate cancer involvement, morphology,… (More)
- Alan Loh Ho, Ravinder Kaur Grewal, +14 authors James A. Fagin
- The New England journal of medicine
- 2013
BACKGROUND
Metastatic thyroid cancers that are refractory to radioiodine (iodine-131) are associated with a poor prognosis. In mouse models of thyroid cancer, selective mitogen-activated protein… (More)
- Fang Fang, Sevin Turcan, +15 authors Timothy A. Chan
- Science translational medicine
- 2011
Cancer-specific alterations in DNA methylation are hallmarks of human malignancies; however, the nature of the breast cancer epigenome and its effects on metastatic behavior remain obscure. To… (More)
- Rohit Mehra, Sooryanarayana Varambally, +5 authors Celina G Kleer
- Cancer research
- 2005
GATA binding protein 3 (GATA3) is a transcriptional activator highly expressed by the luminal epithelial cells in the breast. Here we did a meta-analysis of the available breast cancer cDNA data sets… (More)