Rongjuan Mi

Publications22
h-index11
Citations369
Highly Influential Citations15
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The Hippo pathway effector YAP is an essential regulator of ductal progenitor patterning in the mouse submandibular gland
TLDR
It is shown that Yap-induced Epiregulin signaling promotes the identity of SMG ductal progenitors and that removal of nuclear Yap by Lats1/2-mediated signaling is critical for proper ductal maturation.
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Human endonuclease V as a repair enzyme for DNA deamination.
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Platelet biogenesis and functions require correct protein O-glycosylation
TLDR
It is demonstrated that extended O-glycans are required for normal biogenesis of the platelets as well as the expression and functions of their essential glycoproteins, and that variations in O- Glycosylation may contribute to altered hemostasis.
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Epigenetic Silencing of the Chaperone Cosmc in Human Leukocytes Expressing Tn Antigen*
TLDR
Epigenetic silencing of Cosmc through hypermethylation of its promoter leads to loss of CosMC transcripts in Tn4 cells, an immortalized B cell line from a male patient with a Tn-syndrome-like phenotype, which may be important in understanding aberrant Tn antigen expression in human diseases.
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A novel fluorescent assay for T-synthase activity.
TLDR
This new high-throughput assay allows for facile screening of tumor specimens and other biological material for T-synthase activity and could be used diagnostically.
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Insights from xanthine and uracil DNA glycosylase activities of bacterial and human SMUG1: switching SMUG1 to UDG.
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Lysyl oxidase is associated with increased thrombosis and platelet reactivity.
TLDR
It is found that Pf4-Lox(tg/tg) platelets adhere better to collagen and have greater aggregation response to lower doses of collagen compared with controls, and this demonstrates that LOX enhances platelet activation and thrombosis.
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Identification of Distinct Glycoforms of IgA1 in Plasma from Patients with Immunoglobulin A (IgA) Nephropathy and Healthy Individuals*
TLDR
It is demonstrated that undergalactosylation of O-glycans in IgA1 is not restricted to IgAN and suggested that in vivo inefficiency of T-synthase toward IgA 1 in a subpopulation of B or plasma cells, as well as overall elevation of IgA, may contribute to IgAn pathogenesis.
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Promoters of Human Cosmc and T-synthase Genes Are Similar in Structure, Yet Different in Epigenetic Regulation*
TLDR
It is demonstrated that Cosmc and T-synthase are transcriptionally regulated at a basal level by the specificity protein/Krüppel-like transcription factor family of members, which explains their ubiquitous and coordinated expression, and also indicate that they are differentially epigenetically regulated beyond X chromosome imprinting.
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Repair of deaminated base damage by Schizosaccharomyces pombe thymine DNA glycosylase.
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