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Cell death was examined by studying the spinal cords of rats subjected to traumatic insults of mild to moderate severity. Within minutes after mild weight drop impact (a 10 gm weight falling 6.25 mm), neurons in the immediate impact area showed a loss of cytoplasmic Nissl substances. Over the next 7 d, this lesion area expanded and cavitated. Terminal(More)
We propose a novel significance measure for skeleton pruning, called bending potential ratio (BPR), in which the decision regarding whether a skeletal branch should be pruned or not is based on the context of the boundary segment that corresponds to the branch. By considering this contextual information, we can better evaluate the contribution of the(More)
Frequent embedded subtree pattern mining is an important data mining problem with broad applications. In this paper, we propose a novel embedded subtree mining algorithm, called PrefixTreeESpan (i.e. Prefix-Tree-projected Embedded-Subtree pattern), which finds a subtree pattern by growing a frequent prefix-tree. Thus, using divide and conquer, mining local(More)
Heat-Shock Factor 1 (HSF1), master regulator of the heat-shock response, facilitates malignant transformation, cancer cell survival, and proliferation in model systems. The common assumption is that these effects are mediated through regulation of heat-shock protein (HSP) expression. However, the transcriptional network that HSF1 coordinates directly in(More)
PATIENT Female, 27 FINAL DIAGNOSIS: Central nervous system leukemia Symptoms: Abdominal mass • fever • nausea • vomitting MEDICATION - Clinical Procedure: - Specialty: Hematology. OBJECTIVE Unusual clinical course. BACKGROUND Primary lymphoma of urinary system is an uncommon entity including primary renal lymphoma, primary ureter lymphoma, bladder(More)
OBJECT A glial scar is thought to be responsible for halting neuroregeneration following spinal cord injury (SCI). However, little quantitative evidence has been provided to show the relationship of a glial scar and axonal regrowth after injury. METHODS In this study performed in rats and dogs, a traumatic SCI model was made using a weight-drop injury(More)