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Many motifs along the 1.2 kb myostatin promoter (MSTNpro) in sheep have been found by the MatInspecter program in our recent study. To further verify the role of the motifs and better understand the transcriptional regulation mechanism of the myostatin gene in sheep, the reporter gene EGFP (enhanced green fluorescent protein) was selected and the wild-type(More)
Hypokalemic periodic paralysis (HypoPP) is an autosomal dominant disorder which is characterized by periodic attacks of muscle weakness associated with a decrease in the serum potassium level. The skeletal muscle calcium channel α-subunit gene CACNA1S is a major disease-causing gene for HypoPP, however, only three specific HypoPP-causing mutations,(More)
Dynamic spectrum auction offers the flexibility and capability for bidders to request and acquire unoccupied channels from spectrum license holders. Compared with the conventional auction, spectrum auction allows various buyers to utilize the same channel simultaneously based on their locations, which is denoted as spectrum reusability. In this paper, we(More)
INTRODUCTION Reactive oxygen species are a group of metabolic intermediates produced during oxidative metabolism in eukaryotic cells. They include superoxide anion (O2(-)), hydrogen peroxide (H2O2), hydroxyl radical (·OH), and (1)O2. Of these intermediates, H2O2 is the most stable. Dental pulp cells can be invaded by tooth bleaching, laser radiation, and(More)
Recent case–control studies have identified some loci that are associated with rheumatoid arthritis (RA). Among these, a single nucleotide polymorphism (SNP), Gly307Ser (rs763361), in the CD226 gene was first discovered to confer the risk of RA in populations with European and Colombian ancestry. Because the effect of genetic factors varies in different(More)
In this study, we investigated the hypothesis that regulatory T cells (T(reg)) are involved in the immunomodulatory effects of statins on rheumatoid arthritis (RA) patients. The 12-week study cohort consisted of 55 RA patients and 42 control subjects allocated to either a group treated with atorvastatin (AT) (20 mg/day) or a non-AT group. T(reg) numbers,(More)
The newly emerging event-based social networks (EBSNs) connect online and offline social interactions, offering a great opportunity to understand behaviors in the cyber-physical space. While existing efforts have mainly focused on investigating user behaviors in traditional social network services (SNS), this paper aims to exploit individual behaviors in(More)
A major step is required to integrate critical legal requirements into e-tendering system design. The current systems using ad-hoc security mechanisms do not meet the legal requirements for forming a complex electronic contract. This paper analyses the e-tendering process and its legal obligations. The mapping of these obligations to security policies has(More)