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BACKGROUND This study was undertaken to characterize the vaginal microbiota throughout normal human pregnancy using sequence-based techniques. We compared the vaginal microbial composition of non-pregnant patients with a group of pregnant women who delivered at term. RESULTS A retrospective case-control longitudinal study was designed and included(More)
OBJECTIVE Dysregulation of maternal circulating adipokines has been implicated in several "great obstetrical syndromes" including preeclampsia (PE), small-for-gestational age (SGA) neonate and fetal death (FD). It has been suggested that adipokines provide a molecular link between metabolic derangements and inflammatory response in complicated pregnancies.(More)
Correction We have identified an error in Additional file 1: Table S1 in this article [1], whereby the ethnicities were inverted for some of the subjects. An amended Additional file 1: Table S1 is published here, with the corrected ethnicities highlighted. Additional file 1: Table S1. Taxonomic assignments, total 16S rRNA gene sequences per taxa, and(More)
OBJECTIVE An emerging theme in modern biology is that adipose tissue can respond to metabolic stress, and to inflammatory stimuli, by regulating the secretion of a complex network of soluble mediators, termed adipokines. Adiponectin, the most prevalent circulating adipokine in human, has profound insulin-sensitizing and anti-inflammatory properties. Indeed,(More)
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