Ron Wever

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A set of phosphatases was evaluated for their potential to catalyze the regio-and stereoselective phosphorylation of alcohols using a high-energy inorganic phosphate donor, such as di-, tri-and polyphosphate. Parameters such as type and amount of phosphate donor and pH of the reaction were investigated in order to minimize the thermodynamically favored(More)
The human circadian system controlling the variety of overt 24-h rhythms consists of some different oscillators which are separately self-sustained. Normally, all oscillators run synchronously to each other; under certain external and internal conditions (e.g. increasing score of neuroticism, or old age), however, they run in the steady state with different(More)
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