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Fifty-seven pregnancies in women with antiphospholipid syndrome (APS) are presented. These were treated with s.c. enoxaparin and low dose aspirin. In fourteen pregnancies warfarin was prescribed between weeks 15-34 (warfarin group). The decision to switch to warfarin depended on a morbidity score, and the patient's consent. Neither teratogenicity nor(More)
Many organisations have implemented or are implementing large enterprise systems, like ERP and PDM, for integrating their business functions and streamlining the flow of information. Implementing such systems is very complex, however. In many companies the results envisioned have not or have only partly been achieved. In the literature many explanations can(More)
Antiphospholipid antibody syndrome (APS) is associated with adverse pregnancy outcomes and maternal complications including thrombotic events and early pre-eclampsia. HELLP syndrome (Hemolysis, Elevated Liver enzymes, Low Platelets) represents a unique form in the spectrum of pre-eclampsia. This report describes four patients with pregnancy-associated(More)
This work is a first step towards the application of a Case Based Reasoning (CBR) model to support the management of Enterprise System Implementation (ESI) related organizational change processes. Those processes are characterized by the occurrences of unplanned problems and events, which may lead to major restructuring of the process. We rely on ESI theory(More)
BACKGROUND Drug provocation tests (DPTs) are the gold standard in the diagnosis of β-lactam hypersensitivity. However, no consensus exists on the need for extended provocation tests, even though the effectiveness of the short DPT is relatively low and there has been an increase in the relative incidence of nonimmediate hypersensitivity reactions. (More)
Associations between atopic diseases and lymphocyte antigens seem to be possible, but not certain (for a review see McMichael and McDevitt 1977). Several studies (Levine et al. 1972, Marsh et al. 1973, Yoo et al. 1976, Bruce et al. 1976, Scholtz et al. 1976, Seignalet et al. 1976, Marsh and Bias 1977) have shown a certain association between atopy and(More)
INTRODUCTION Emergence delirium (ED) is a common problem among children and adults recovering from general anesthesia after surgery. Its symptoms include psychomotor agitation, hallucinations, and aggressive behavior. The phenomenon, which is most probably an adverse effect of general anesthesia agents, harms the recovery process and endangers the physical(More)
To increase colonoscopy competence in ambiguous situations (e.g. the existence of flat polyps), an explicit in situ (at real time) diagnosis at the molecular level is required. We have previously shown that the affinity of fluorescent cationic polyacrylamide (Flu-CPAA) to malignant regions in the colon mucosa can be improved by conjugating the recognition(More)
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