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To investigate the role of modified low-density lipoproteins (LDL) in the pathogenesis of diabetic retinopathy, we studied the cytotoxicity of normal and mildly modified human LDL to bovine retinal capillary endothelial cells and pericytes in vitro. Pooled LDL was incubated (in phosphate-buffered saline-EDTA, 3 days, 37 degrees C) under 1) nitrogen with(More)
The paper presents the C-Sim simulation tool that enables an experimental evaluation (i.e. testing) of parallel and distributed programs behavior using their close-toreality C-language source code and a simulated operational environment. 1. Simulation based method of parallel programs testing The method uses discrete-time process-oriented simulation model(More)
OBJECTIVE To compare platelet plasminogen activator inhibitor 1 (PAI-1) concentration in type II diabetic patients and healthy control subjects. RESEARCH DESIGN AND METHODS We studied a group of 12 diabetic patients whose disease was controlled by diet or sulfonylurea therapy and a group of 17 nondiabetic control subjects. All subjects were free of(More)
OBJECTIVE To compare platelet plasminogen activator inhibitor 1 (PAI-1) release in type II diabetic patients and healthy control subjects. RESEARCH DESIGN AND METHODS We studied a group of 27 diabetic patients and a group of 16 nondiabetic control subjects. Whole-blood platelet aggregation, defined as a decrease in platelet count during shaking (180 rpm)(More)
C-Sim is a programming tool for simulation of discrete processes using a method of pseudoparallel processes. It is an extension of C language obtained by including SIMULA-like macros and functions. C-Sim uses a special C-functions and C-macros library. The typical application area of C-Sim is functional validation of distributed, parallel and fault-tolerant(More)
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