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Prostate segmentation in 3-D transrectal ultrasound images is an important step in the definition of the intra-operative planning of high intensity focused ultrasound (HIFU) therapy. This paper presents two main approaches for the semi-automatic methods based on discrete dynamic contour and optimal surface detection. They operate in 3-D and require a(More)
Dengue is an important mosquito borne viral disease in Martinique Island (French West Indies). The viruses responsible for dengue are transmitted by Aedes aegypti, an indoor day-biting mosquito. The most effective proven method for disease prevention has been by vector control by various chemical or biological means. Unfortunately insecticide resistance has(More)
PURPOSE Upper tract urothelial carcinoma (UTUC) is a rare and poorly investigated disease. Intense collaborative efforts have increased our knowledge and improved the management of the disease. The objective of this review was to discuss recent advances and unmet needs in UTUC. METHODS A non-systematic Medline/PubMed literature search was performed on(More)
OBJECTIVE This study focuses on laparoscopic nephrectomy for autosomal dominant polycystic kidney disease (ADPKD). MATERIAL AND METHODS We retrospectively reviewed 21 consecutive patients who had previously undergone laparoscopy between 2007 and 2010. Data were compared to that obtained from 19 consecutive patients who had open surgery between 2004 and(More)
OBJECTIVE Several retrospective studies with small cohorts reported neutrophil-to-lymphocyte ratio (NLR) as a prognostic marker in upper tract urothelial carcinoma (UTUC) following radical nephroureterectomy (RNU). We aimed at validating the predictive and prognostic role of NLR in a large multi-institutional cohort. METHODS Preoperative NLR was assessed(More)
PURPOSE To assess the role of E-cadherin as prognostic biomarker in upper tract urothelial carcinoma (UTUC) in a large multi-institutional cohort of patients. METHODS Immunohistochemistry technique was used to evaluate E-cadherin expression in 678 patients with unilateral, sporadic UTUC treated with RNU. E-cadherin expression was considered decreased if(More)
Urothelial carcinoma of the bladder (UCB) and upper tract (UTUC) are now established as two distinct entities with differences in anatomical, biological and molecular characteristics. Indeed, specific clinical guidelines have been produced for each of them to guide clinicians (1-3). Despite their status of " disparate twins " , UCB and UTUC still share(More)
Locally advanced (T3b, T4 and N1-N3) and metastatic urothelial bladder cancer (BCa) is a lethal disease with poor survival outcomes. Combination chemotherapy remains the treatment of choice in patients with metastatic disease and an important part of treatment in addition to radical cystectomy (RC) in patients with locally advanced tumour. Approximately(More)
Preface Contemporary concepts and controversies in the diagnosis and management of urothelial carcinoma Urothelial carcinoma (UC) is the fourth most common cancer in men in the Western world and the second most frequent malignancy of the urinary tract after prostate cancer. It can be located in the lower (bladder and urethra) or upper (pyelo-caliceal(More)