We report new results on blood flow modeling over large volumes of cortical gray matter of primate brain. We propose a network method for computing the blood flow, which handles realistic boundary conditions, complex vessel shapes, and complex nonlinear blood rheology. From a detailed comparison of the available models for the blood flow rheology and the… (More)
Vascular domains have been described as being coupled to neuronal functional units enabling dynamic blood supply to the cerebral cyto-architecture. Recent experiments have shown that penetrating arterioles of the grey matter are the building blocks for such units. Nevertheless, vascular territories are still poorly known, as the collection and analysis of… (More)
In this note, the existing porousMultiphaseFoam toolbox, developed initially for any two-phase flow in porous media is extended to the specific case of the Richards' equation which neglect the pressure gradient of the non-wetting phase. This model is typically used for saturated and unsaturated groundwater flows. A Picard's algorithm is implemented to… (More)
3D computational fluid dynamics (CFD) in patient-specific geometries provides complementary insights to clinical imaging, to better understand how heart disease, and the side effects of treating heart disease, affect and are affected by hemodynamics. This information can be useful in treatment planning for designing artificial devices that are subject to… (More)
Cerebral blood flow (CBF) is the most common parameter for the quantification of brain's function. Literature data indicate a widespread dispersion of values that might be related to some differences in the measurement conditions that are not properly taken into account in CBF evaluation. Using recent high-resolution imaging of the complete cortical… (More)
OATAO is an open access repository that collects the work of Toulouse researchers and makes it freely available over the web where possible. To cite this version : Guibert, Romain and Fonta, Caroline and Plouraboué, Franck From cerebral blood flow modeling to vascular units map in primate cortex.
OATAO is an open access repository that collects the work of Toulouse researchers and makes it freely available over the web where possible. Abstract The modeling of blood flows confined in micro-channels or micro-capillary beds depends on the interactions between the cell-phase, plasma and the complex geometry of the network. In the case of capillaries or… (More)
Blood rheology is complex and nonlinear. The effective viscosity variations are important due to red blood cells packing inside capillaries, the socalled FåhraeusLindquist effect, whilst concomitantly phase segregation appears in bifurcations. We have performed direct numerical simulations of different nonlinear rheological models of the blood on… (More)