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- Thomas Efferth, Achille Benakis, +8 authors Manfred Marschall
- Free radical biology & medicine
- 2004
Iron(II) heme-mediated activation of the peroxide bond of artemisinins is thought to generate the radical oxygen species responsible for their antimalarial activity. We analyzed the role of ferrous… (More)
- Thomas Efferth, Rolf Rauh, +6 authors Bernd Kaina
- Biochemical pharmacology
- 2004
Cancer chemotherapy is often limited by patient's toxicity and tumor drug resistance indicating that new drug development and modification of existing drugs is critical for improving the therapeutic… (More)
- Thomas Efferth, Stefan Kahl, +6 authors Rudolf Bauer
- Molecular cancer therapeutics
- 2008
The cure from cancer is still not a reality for all patients, which is mainly due to the limitations of chemotherapy (e.g., drug resistance and toxicity). Apart from the high-throughput screening of… (More)
- Rolf Rauh, Stefan Kahl, Herbert Boechzelt, Rudolf Bauer, Bernd Kaina, Thomas Efferth
- Chinese medicine
- 2007
Herbal medicine is one of the forms of traditional medical practice. Traditional Chinese medicine (TCM) and traditional Vietnamese medicine (TVM) are well-known for their long-standing tradition of… (More)
- Achille Benakis, Marta Rodriguez Romero, +6 authors Bernd Kaina
- 2004
*Center for Molecular Biology, University of Heidelberg, Heidelberg, Germany; yDepartment of Pharmacology, University of Geneva, Geneva, Switzerland; zDepartment of Biochemistry and Molecular… (More)