Rolf Marquardt

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It is widely accepted that a disturbed blood supply of the optic disc may cause (in addition with an increased intraocular pressure) optic nerve fibre damage. Therefore we measured ocular perfusion pressures in 79 healthy subjects. In 18 patients with low tension glaucoma, in 27 patients suffering from ocular hypertension and in 49 glaucoma (OAG) patients.(More)
In 30 subjects without ophthalmological disease the corneal contact time of a new artificial polyacrylic-based tear gel (Vidisic, produced by Dr. Mann, Berlin) was compared with a well-known artificial polyvinyl alcohol-based tear solution. The Vidisic concentration remained in the corneal tear film 7 times longer than the substance it was compared with. In(More)
Basic tear secretion (Schirmer test) and tear stability (fluorescein break-up time (BUT) were determined in 121 healthy subjects and related to age and goblet cell count. None of the eyes thus investigated had any inflammatory or degenerative changes of the lids, conjunctiva or cornea. A low goblet cell count was found in subjects with a short BUT but a(More)
  • R Marquardt
  • Klinische Monatsblätter für Augenheilkunde
  • 1986
Critical appraisal of the most important testing methods for diagnosing normal and disturbed stability of the tear film meniscus. Only a carefully compiled history, a thorough inspection of the eye and several tests to determine the type and severity of the disorder can provide information about the disturbed stability of the tear film meniscus.
The effect of Vidisic (a new jelly artificial tear solution) and an ointment basing on Dexpanthenol on the tear production and the tear film stability was studied both on patients in the intensive care units (ICU) and during operations. In 10 relaxed and ventilated patients of the ICU there was no significant change in the tear production after application(More)
Traditional beta-blocking eye drops preserved with benzalkonium chloride show an adverse effect on the precorneal tear film, which can be measured by checking the break-up-time (BUT). To decide, whether this adverse effect is caused more by the beta-blocking drug or the preservative, we tested the influence of timolol eye drops without preservative in(More)
The influence of topically applied clonidine 0.125% on ocular hemodynamics was investigated in ten patients with open-angle glaucoma and ten healthy volunteers, using a new, differentiated method. Ocular perfusion pressures were determined by Ulrich's method of oculo-oscillodynamography. Following monocular application of clonidine 0.125% eye drops a clear(More)