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In the phosphorelay signal transduction system for sporulation initiation in Bacillus subtilis, the opposing activities of histidine kinases and aspartyl phosphate phosphatases determine the cell's decision whether to continue with vegetative growth or to initiate the differentiation process. Regulated dephosphorylation of the Spo0A and Spo0F response(More)
Bacillus subtilis growing at 37 degrees C synthesizes, almost exclusively, saturated fatty acids. However, when a culture growing at 37 degrees C is transferred to 20 degrees C, the synthesis of unsaturated fatty acids is induced. The addition of the DNA gyrase inhibitor novobiocin specifically prevented the induction of unsaturated fatty acid synthesis at(More)
By considering two important factors involved in the codon-anticodon interactions, the hydrogen bond number and the chemical type of bases, a codon array of the genetic code table as an increasing code scale of interaction energies of amino acids in proteins was obtained. Next, in order to consecutively obtain all codons from the codon AAC, a sum operation(More)
Kinase A is the sensor histidine kinase responsible for processing postexponential phase information and providing phosphate input to the phosphorelay that activates developmental transcription via phosphorylated Spo0A. A protein inhibitor, KipI, of kinase A was discovered encoded in an operon of genes of unknown function but regulated by the availability(More)
s icher t s ind, we rden n a c h s t e h e n d einige K u r v e n der pho to m e t r i s c h e n A u s w e r t u n g des E lek t rophoreses t r e i f ens wiedergegeben (Fig. 2), die die E x t i n k t i o n als F u n k t i o n der W a n d e r u n g s s t r e c k e dars te l len . Alle K u r v e n zeigen zuni iehs t an der Aufsa tzs te l l e e inen s te i len(More)
The rapid growing of applications of Advanced Transport Telematic (ATT) systems in recent years is generating an increasing request for tools to help in system design and assessment. Microscopic traffic simulation has proven to be one of the most useful tools to achieve these objectives, and thus microscopic traffic simulation has become an ever increasing(More)
A hallmark of sporulation of Bacillus subtilis is the formation of two distinct cells by an asymmetric septum. The developmental programme of these two cells involves the compartmentalized activities of sigmaE in the larger mother cell and of sigmaF in the smaller prespore. A potential role of de novo lipid synthesis on development was investigated by(More)
We have produced and characterized by physiological and enzymatic analyses pantothenate (pan) auxotrophs of Bacillus subtilis. panB auxotrophs are deficient in ketopantoate hydroxymethyltransferase, whereas panE mutants lack ketopantoic acid reductase. The pan mutations were mapped by phage PBS1-mediated two-factor crosses and found to be located in the(More)
Bacillus subtilis synthesizes, almost exclusively, saturated fatty acids, when grown at 37 degrees C. When cultures were transferred from 37 degrees C to 20 degrees C, a chloramphenicol- and rifampicin-sensitive synthesis of a C-16 unsaturated fatty acid was observed. Synthesis of this compound reached a plateau after 5 h at 20 degrees C, reaching levels of(More)
" D o m i n a n t h e m o m e l i a " (Dh) is a m u t a n t gene of t h e house m o u s e caus ing s t r ik ing ske le ta l and viscera l abnormal i t i e s l ) . Whi l e these are s imi lar in p a r t to those of t he g roup of " l u x o i d " m u t a n t s (skeletal ly, Dh he te rozygo te s are a f fec ted m u c h t h e s a m e w a y as luxa te , lx a n d(More)