Rolf A A Pullens

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Physiological wall shear rates and stresses in vessel culture or tissue engineering are relevant for maintaining endothelial cell (EC) integrity. To this end, the culture medium should have an appropriate viscosity. The viscosity of a standard culture medium was increased using xanthan gum (XG) and compared with literature data on whole blood, resulting in(More)
Tissue engineering of small diameter (<5 mm) blood vessels is a promising approach to develop viable alternatives for autologous vascular grafts. Development of a functional, adherent, shear resisting endothelial cell (EC) layer is one of the major issues limiting the successful application of these tissue engineered grafts. The goal of the present study(More)
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