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OBJECTIVE To establish a new approach for determination of the optimal apical preparation size (APS). STUDY DESIGN After preflaring 212 root canals from 80 extracted molars, electronic working length (WL) was measured to establish where the apical preparation size (APS) should be determined. Subsequently, nontapered, noncutting special instruments were(More)
BACKGROUND Use of oral antiseptics decreases the bacterial load in the oral cavity. OBJECTIVE To compare the antimicrobial activity of 3 novel oral antiseptics with that of chlorhexidine, which is considered the "gold standard" of oral hygiene. DESIGN Comparative in vitro study. METHODS Four common oral microorganisms (Streptococcus sanguinis,(More)
The purpose of this study was to investigate a three-species in vitro biofilm with peri-implantitis-related bacteria for its variability and metabolic activity. Streptococcus sanguinis, Fusobacterium nucleatum, and Porphyromonas gingivalis were suspended in simulated body fluid containing 0.2% glucose to form biofilms on polished, protein-coated(More)
Human leukocyte antigens (HLA) are crucial components of host defense against microbial challenge but the associations of HLA types with oral infectious diseases have not been studied in detail. This prospective cross-sectional study examined associations of HLA-A, -B and -DRB1 types with common oral diseases in a healthy Swiss adult population. 257(More)
OBJECTIVES The intraoral transmission of cariogenic and periodontopathogenic species seems to be facilitated by contaminated toothbrushes and other oral hygiene devices. The aim of this investigation was to analyze the in vitro retention and survival rate of Streptococcus mutans and Streptococcus sanguinis on different toothbrushes. The impacts of human(More)
Within the framework of a gingivitis study the sulcus fluid flow rate (SFFR) at the lower and upper premolars of 9 subjects was determined with the assistance of Periotron 6000. The measurements were conducted at days 0, 7, 14 and 21 with the aim to compare the SFFR after 3 minutes (Löe and Holm-Pedersen 1965, Rüdin et al. 1970) with the measurements of(More)
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