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AIMS To provide 12-month prevalence and disability burden estimates of a broad range of mental and neurological disorders in the European Union (EU) and to compare these findings to previous estimates. Referring to our previous 2005 review, improved up-to-date data for the enlarged EU on a broader range of disorders than previously covered are needed for(More)
BACKGROUND The spectrum of disorders of the brain is large, covering hundreds of disorders that are listed in either the mental or neurological disorder chapters of the established international diagnostic classification systems. These disorders have a high prevalence as well as short- and long-term impairments and disabilities. Therefore they are an(More)
Seven systems for the diagnosis of schizophrenia were compared in their ability to predict short-term outcome at follow-up: with each other, with selected specific symptoms, and with a simple additive composite symptom score. None of the systems nor the symptoms predicted strongly, but DSM-III and Schneiderian First Rank Symptoms and the composite score(More)
We compared the joint frequencies and reliabilities of the following sets of criteria for the diagnosis of schizophrenia: the New Haven Schizophrenia Index: the Carpenter, Strauss, Bartko (4-, 5-, 6-, and 7-item) system; DSM-III; Research Diagnostic Criteria (RDC; full and chronic); the Feighner system; and the 1975 criteria of Taylor and Abrams. The(More)
This paper describes a student project which is a major part of a senior level Operating Systems course at the Federal Institute of Technology in Lausanne. The project consists in conceiving and implementing an entire Operating System, where user jobs benefit from a simulated paged virtual memory on a DEC-LSI/11 based microprocessor. Students program in(More)
A series of 57 extended pedigrees with high density of bipolar affective disorder is described. Ascertainment and diagnostic procedures are documented and simulation studies to assess statistical power are carried out. The pedigrees, obtained in the US and Israel, are comprised of 1508 adult individuals with best estimate consensus diagnoses (12-71(More)
Over the last 20 years, whether as an overarching concept, or as shorthand for specific interventions, 'harm reduction' has changed the way we think about and respond to drug problems in Europe. Debates continue today about what sort of interventions legitimately fall under the heading of harm reduction, and what value they bring. However, measures that(More)