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Proliferation and survival of Hodgkin and Reed/Sternberg (HRS) cells, the malignant cells of classical Hodgkin lymphoma (cHL), are dependent on constitutive activation of nuclear factor kappaB (NF-kappaB). NF-kappaB activation through various stimuli is negatively regulated by the zinc finger protein A20. To determine whether A20 contributes to the(More)
Many financial institutions have deployed CAPTCHAs to protect their services (e.g., e-banking) from automated attacks. In addition to CAPTCHAs for login, CAPTCHAs are also used to prevent malicious manipulation of e-banking transactions by automated Man-in-the-Middle (MitM) attackers. Despite serious financial risks, security of e-banking CAPTCHAs is(More)
In this paper, we propose hPIN/hTAN, a low-cost hardware token based PIN/TAN system for protecting e-banking systems against the strong threat model where the adversary has full control over the user's computer. This threat model covers various kinds of attacks related to untrusted terminal computers, such as keyloggers, screen scrapers, session hijackers,(More)
—Recently a new human authentication scheme called PAS (predicate-based authentication service) was proposed , which does not require the assistance of any supplementary device. The main security claim of PAS is to resist passive adversaries who can observe the whole authentication session between the human user and the remote server. In this paper we show(More)
—In ICC2008 and subsequent work, Lei et al. proposed a user authentication system (virtual password system), which is claimed to be secure against identity theft attacks, including phishing, keylogging and shoulder surfing. Their au-thentication system is a challenge-response protocol based on a randomized linear generation function, which uses a random(More)
We propose a new approach to commutative watermarking-encryption (CWE). A permutation cipher is used to encrypt the mul-timedia data, which leaves the global statistics of the multimedia data intact. Therefore, any non-localized watermarking scheme that depends only on global statistics of the multimedia data can be combined with the permutation cipher to(More)
Nuclear factor-κB (NF-κB) controls genes involved in normal lymphocyte functions, but constitutive NF-κB activation is often associated with B cell malignancy. Using high-throughput whole transcriptome sequencing, we investigated a unique family with hereditary polyclonal B cell lymphocytosis. We found a novel germline heterozygous missense mutation (E127G)(More)
Adult T cell leukemia/lymphoma (ATLL) is an aggressive malignancy caused by human T cell lymphotropic virus type-I (HTLV-I) without curative treatment at present. To illuminate the pathogenesis of ATLL we performed whole transcriptome sequencing of purified ATLL patient samples and discovered recurrent somatic mutations in CCR4, encoding CC chemokine(More)