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- Gyula Kispál, Peter Csere, Corinna Prohl, Roland Lill
- The EMBO journal
- 1999
Iron-sulfur (Fe/S) cluster-containing proteins catalyse a number of electron transfer and metabolic reactions. Little is known about the biogenesis of Fe/S clusters in the eukaryotic cell. Here, we… (More)
- Aleix Navarro-Sastre, Frederic Tort, +18 authors Roland Lill
- American journal of human genetics
- 2011
We report on ten individuals with a fatal infantile encephalopathy and/or pulmonary hypertension, leading to death before the age of 15 months. Hyperglycinemia and lactic acidosis were common… (More)
- Ulrich Mühlenhoff, Nadine Richter, Ophry Pines, Antonio J. Pierik, Roland Lill
- The Journal of biological chemistry
- 2011
Most eukaryotes contain iron-sulfur cluster (ISC) assembly proteins related to Saccharomyces cerevisiae Isa1 and Isa2. We show here that Isa1 but not Isa2 can be functionally replaced by the… (More)
- Julian C. Rutherford, Luis F. Ojeda, Janneke Balk, Ulrich Mühlenhoff, Roland Lill, Dennis R Winge
- The Journal of biological chemistry
- 2005
Two transcriptional activators, Aft1 and Aft2, regulate iron homeostasis in Saccharomyces cerevisiae. These factors induce the expression of iron regulon genes in iron-deficient yeast but are… (More)
- Heike Lange, Thomas Lisowsky, Jana Gerber, Ulrich Mühlenhoff, Gyula Kispál, Roland Lill
- EMBO reports
- 2001
Biogenesis of Fe/S clusters involves a number of essential mitochondrial proteins. Here, we identify the essential Erv1p of Saccharomyces cerevisia mitochondria as a novel component that is… (More)
- K Kuenkele, Susanne Heins, +7 authors Walter Neupert
- Cell
- 1998
The preprotein translocase of the outer membrane of mitochondria (TOM complex) facilitates the recognition, insertion, and translocation of nuclear-encoded mitochondrial preproteins. We have purified… (More)
- Luis D Ojeda, Greg L Keller, Ulrich Muhlenhoff, Julian C. Rutherford, Roland Lill, Dennis R Winge
- The Journal of biological chemistry
- 2006
The transcription factors Aft1 and Aft2 from Saccharomyces cerevisiae regulate the expression of genes involved in iron homeostasis. These factors induce the expression of iron regulon genes in… (More)
- Roland Lill, Ulrich Mühlenhoff
- Annual review of biochemistry
- 2008
Iron-sulfur (Fe/S) proteins are involved in a wide variety of cellular processes such as enzymatic reactions, respiration, cofactor biosynthesis, ribosome biogenesis, regulation of gene expression,… (More)
- Ulrich Mühlenhoff, Jana Gerber, Nadine Richhardt, Roland Lill
- The EMBO journal
- 2003
The mitochondrial proteins Isu1p and Isu2p play an essential role in the maturation of cellular iron-sulfur (Fe/S) proteins in eukaryotes. By radiolabelling of yeast cells with 55Fe we demonstrate… (More)
- Ulrich Mühlenhoff, Sabine Molik, +9 authors Roland Lill
- Cell metabolism
- 2010
Iron is an essential nutrient for cells. It is unknown how iron, after its import into the cytosol, is specifically delivered to iron-dependent processes in various cellular compartments. Here, we… (More)