Roland Hellman

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Fahr's disease is histopathologically characterized by massive bilateral calcifications of the cerebral basal ganglia, the dentate nuclei of the cerebellum and both the cerebral and cerebellar cortices. We report a case of Fahr's disease in which a 99mTc-hexamethyl-propylenamine oxime (99mTc-HMPAO) brain SPECT study was used to evaluate regional cerebral(More)
To enable a more quantitative diagnosis of senile dementia of the Alzheimer type (SDAT), the authors developed and tested a semiautomated method to define regions of interest (ROIs) to be used in quantitating results from single photon emission computed tomography (SPECT) of regional cerebral blood flow performed with N-isopropyl iodine-123-iodoamphetamine.(More)
Single photon emission computerized tomography (SPECT) studies were performed on 34 manifest Huntington's disease (HD) patients at various stages of clinical pathology ranging from early chorea to late dystonia with or without signs of dementia and 12 pre-symptomatic patients with abnormal terminal CAG expansions. Thirty HD patients with obvious clinical(More)
In dichotic listening tasks, the (dominant) right ear's superiority in processing verbal stimuli has been attributed to its direct anatomic connection with the left dominant hemisphere. The role played by extralinguistic factors, such as attention and functional tuning of the associated cortical structures, has not been carefully examined. This(More)
Vascular constriction is said to account for a variety of clinical effects of cocaine. High-resolution 99mTc-hexamethylpropylene amine oxime single photon emission computed tomographic (SPECT) scans, which measure cerebral blood flow, were used to determine whether neonatal brain perfusion deficits are present in newborns with confirmed cocaine exposure.(More)
A technique for simultaneously measuring pulsation, translation and diffusion of a radioactive tracer in the spinal cerebrospinal fluid (CSF) has been described. To evaluate the accuracy and precision of this method for measuring CSF oscillation in the spine, an apparatus was designed that moved a radioactive source sinusoidally with known amplitude along a(More)
In dichotic listening tasks, the (dominant) right ear's superiority in processing verbal stimuli has been attributed to its direct access to the linguistically dominant left hemisphere. The roles played by the extralinguistic factors, such as induced attentiveness and functional tuning of the auditory system, have not been carefully examined. The evidence(More)
Regional CBF (rCBF) images obtained from xenon-enhanced computed tomography (XeCT) and single-photon emission computed tomography (SPECT) with N-isopropyl-p-[123I]iodoamphetamine (IMP) done with a rotating gamma-camera were compared in nine patients. Both XeCT and SPECT/IMP demonstrated flow abnormalities at all sites of infarction identified by CT, while(More)
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