Roland Axmann

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There has been a consistent gap in understanding how TNF-α neutralization affects the disease state of arthritis patients so rapidly, considering that joint inflammation in rheumatoid arthritis is a chronic condition with structural changes. We thus hypothesized that neutralization of TNF-α acts through the CNS before directly affecting joint inflammation.(More)
This functional magnetic imaging study investigated the functional implications of genetic modification and pharmacological intervention on cerebral processing of heat-induced nociception in mice. Comparing dynorphin-overexpressing dream(-/-) with wild-type mice, smaller activated cortical and limbic brain structure sizes could be observed. Moreover,(More)
Koi herpesvirus disease (KHVD) is a highly contagious viral illness causing significant morbidity and mortality in common carp (Cyprinus carpio). KHVD has been confirmed in almost all countries around the world except Australia. KHV has been previously detected in the Czech Republic based on PCR screening but with no clinical signs of KHVD. An outbreak of(More)
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