Roi Villar-Vázquez

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PURPOSE Cancer-associated fibroblasts (CAF) are essential components of the stroma that play a critical role in cancer progression. This study aimed to identify novel CAFs markers that might contribute to the invasion and the prognosis of colorectal cancer. EXPERIMENTAL DESIGN The azoxymethane/dextran sodium sulfate mouse model of sporadic colon cancer(More)
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Our knowledge of cancer-associated stroma is rather limited in comparison with cancer epithelial cells. Stroma constitutes the cancer microenvironment that nurtures cancer cells and facilitates invasion and metastasis. Moreover, stromal myofibroblasts have(More)
Although autoantibody detection has been proposed for diagnosis of colorectal cancer, little is known about their initial production and development correlation with cancer progression. Azoxymethane/dextran sodium sulfate (AOM/DSS)-treated mice developed colon adenocarcinoma in the distal colon similar to human sporadic colon cancer. We assessed this model(More)
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