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PURPOSE To investigate clinical, anatomic, and electrophysiologic response after single intravitreal injection of bevacizumab for macular edema attributable to retinal vein occlusion. DESIGN Prospective nonrandomized, interventional case series. METHODS Twenty-one patients with macular edema attributable to vein occlusion received intravitreal injection(More)
PURPOSE To investigate macular changes in acute retinopathy of prematurity (ROP). METHODS Fifty-four premature infants with ROP and 20 controls underwent routine ROP screening with indirect ophthalmoscopy and imaging. A tabletop spectral domain optical coherence tomography (SD-OCT) scanner (Spectralis; Heidelberg Engineering, Heidelberg, Germany) was(More)
PURPOSE To report ocular manifestations associated with chikungunya. DESIGN Retrospective, nonrandomized, observational case series. PARTICIPANTS Nine chikungunya patients with ocular involvement. METHODS All patients with chikungunya infection presenting with ocular complaints from September 2006 to October 2006 were included in the study. The(More)
AIMS/BACKGROUND Mechanical and vascular factors may both contribute to glaucoma. This study investigated the relation of mechanical to vascular factors by examining how acute IOP elevation altered flow velocities in the central retinal and ophthalmic arteries. METHODS IOP was elevated from a baseline near 14 to approximately 45 mm Hg using suction(More)
PURPOSE To study the effect of different protocols of collagen cross-linking on visual, refractive, and tomographic parameters in patients with progressive keratoconus. DESIGN Prospective randomized interventional study. METHODS In this study, 138 eyes of 138 patients with progressive keratoconus underwent corneal collagen cross-linking (CXL). Following(More)
Purpose To evaluate with electrophysiological responses and Optical Coherence Tomography (OCT), the short term functional and structural effects at the macula following intravitreal injection of bevacizumab for macular edema. Methods Prospective, non-randomized, interventional case study. In total, 17 eyes of 17 patients with macular edema due to vein(More)
Foveal hypoplasia and optic nerve misrouting are developmental defects of the visual pathway and only co-occur in connection with albinism; to date, they have only been associated with defects in the melanin-biosynthesis pathway. Here, we report that these defects can occur independently of albinism in people with recessive mutations in the putative(More)
PURPOSE To evaluate the effectiveness and safety of accelerated corneal collagen cross-linking (ACXL) in patients below 14 years of age with progressive keratoconus. MATERIALS AND METHODS Thirty eyes of 18 patients with established progressive keratoconus underwent preoperative and postoperative visual acuity assessment, topography, and specular(More)
PURPOSE To evaluate the surgical outcomes of microthin intracorneal ring segment (INTACS) implantation in advanced keratoconus. METHODS INTACS implantation was performed in eyes with advanced keratoconus. The main outcome measures were uncorrected visual acuity, best spectacle-corrected visual acuity, change in mean refractive spherical equivalent (MRSE),(More)
Chikungunya is a self-limited, systemic viral infection that has been a major health problem since the past few years. Ocular manifestations of the disease have become more prevalent in the recent years. Currently, there is neither a specific treatment nor vaccine available for chikungunya fever. This review highlights the current understanding on the(More)