Learn More
  • R Rao
  • 2000
OBJECTIVES To examine the relationship between depression and cerebrovascular disease in three distinct settings: depression in established cerebrovascular disease, cerebrovascular disease in established depression and depression in vascular dementia. METHODS Medline, EMBASE, PsychLit and PsychInfo databases were scanned to locate relevant articles. Data(More)
BACKGROUND AND PURPOSE An increasing body of literature suggests a role for clinically "silent" cerebrovascular disease in the pathogenesis of cognitive impairment. Such pathology commonly occurs in the absence of stroke. The main aim of the study was to examine neuropsychological impairment associated with cerebrovascular and peripheral vascular disease(More)
BACKGROUND The extent to which genetic effects on the different subtypes of small (SVD) and large vessel disease (LVD) ischaemic stroke differ remains controversial. METHODS A comprehensive genetic meta-analysis of all genes investigated by ischaemic stroke subtype was conducted. Odds ratio (OR) and 95% confidence intervals (CI) were determined for each(More)
BACKGROUND Although depression has a recognised association with stroke, the role of "silent" cerebrovascular pathology associated with carotid stenosis and peripheral vascular disease remains unexplored. METHODS Four groups of 25 community residents aged 65 and over were recruited, comprising first anterior circulation stroke, carotid stenosis(More)
The term 'Vascular Dementia' remains popular as a diagnostic entity, since it encompasses a variety of vascular pathologies. This is in stark contrast to many clinical classificatory systems that weight their definitions strongly towards stroke alone. A diagnosis of vascular dementia is complicated by compounding factors that reduce both the validity and(More)
OBJECTIVES To determine the prevalence of primitive reflexes (frontal release signs) in elderly community residents with cerebrovascular disease and to examine their relationship with neuropsychological and mood-related variables. METHODS Three groups of 25 people over 65 with anterior circulation stroke, transient ischaemic attack (TIA) and a control(More)
  • 1