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APPLIED BIOLOGICAL SCIENCES Correction for “Design and formulation of functional pluripotent stem cell-derived cardiac microtissues,” by Nimalan Thavandiran, Nicole Dubois, Alexander Mikryukov, Stéphane Massé, Bogdan Beca, Craig A. Simmons, Vikram S. Deshpande, J. Patrick McGarry, Christopher S. Chen, Kumaraswamy Nanthakumar, Gordon M. Keller, Milica(More)
The purpose of this study was to elucidate the role of nucleotide binding oligomerization domain-containing protein 2 (NOD2) signaling in atherosclerosis and periodontal bone loss using an Apolipoprotein E(-/-) (ApoE(-/-)) mouse model based on the proposed role of NOD2 in inflammation. NOD2(-/-)ApoE(-/-) and ApoE(-/-) mice fed a standard chow diet were(More)
AIM The purpose of this study was to assess the role of anti-bone resorptive agents and an anti-inflammatory compound in murine Porphyromonas gingivalis (P. gingivalis)-induced periodontitis. MATERIAL AND METHODS Six randomly assigned groups were administered vehicle (saline, control) (n = 6), P. gingivalis infection only (untreated) (n = 6), human-Fc (n(More)
Conversion of adenosine to inosine is a frequent type of RNA editing, but important details about the biology of this conversion remain unknown because of a lack of imaging tools. We developed inoFISH to directly visualize and quantify adenosine-to-inosine-edited transcripts in situ. We found that editing of the GRIA2, EIF2AK2, and NUP43 transcripts is(More)
APPLIED BIOLOGICAL SCIENCES Correction for “Design and formulation of functional pluripotent stem cell-derived cardiac microtissues,” by Nimalan Thavandiran, Nicole Dubois, Alexander Mikryukov, Stéphane Massé, Bogdan Beca, Craig A. Simmons, Vikram S. Deshpande, J. Patrick McGarry, Christopher S. Chen, Kumaraswamy Nanthakumar, Gordon M. Keller, Milica(More)
The synthesis and anticonvulsant activity of nipecotic acid esters (1a-1f) have been previously reported. It was thought that these prodrug esters underwent hydrolytic conversion to 1 which inhibited GABA uptake, and that both 1 and an intact ester may have caused inhibition of GABA uptake which resulted in the anticonvulsant activity. There is, however, no(More)
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