Rohan Shah

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Olfactory receptors (ORs) form a large family of G protein-coupled receptor proteins (GPCRs) responsible for sensing the ambient chemical environment. The molecular recognition strategies used by ORs to detect and distinguish odorant molecules are unclear. Here, we investigated the variable of odorant carbon chain conformation for an established odorant-OR(More)
We present a novel estimator for map construction in the presence of segregation distortion which is highly computationally efficient. For multi-parental designs this estimator outperforms methods that do not account for segregation distortion, at no extra computational cost. Inclusion of genetic markers exhibiting segregation distortion in a linkage map(More)
Glucocorticoid remediable aldosteronism (GRA) is rare familial form of primary aldosteronism characterized by a normalization of hypertension with the administration of glucocorticoids. We present a case of GRA and thoracoabdominal aneurysm complicated by multiple aortic dissections requiring complex surgical and endovascular repairs. Registry studies have(More)
Objectives Diarrhea is common in patients coming to Emergency Department (ED), especially among those who receive antibiotics. Clostridium difficile is the most commonly identified organism for antibiotic associated diarrhea. Because of the frequent use of broad-spectrum antibiotics , the incidence of C. difficile-associated diarrhea (CDAD) has risen(More)
Amelogenesis imperfecta (AI) is a group of hereditary disorders that affect the quality and/or quantity of dental enamel. This paper describes the clinicopathological features of a patient who was born of nonconsanguineous parents and who presented with oral alterations, including yellow and misshapen teeth, intrapulpal calcifications, delayed tooth(More)
Spatial statistical models are of considerable practical and theoretical interest. However, there has been little work on rare-event probability estimation for such models. In this paper we present a conditional Monte Carlo algorithm for the estimation of the probability that random graphs related to Bernoulli and continuum percolation are connected.(More)
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