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The title compounds (I) and (II) are the first C-7 alkylated caprolactam natural products reported.
A novel pyridoacridine alkaloid 12-deoxyascididemin (I) is isolated together with the known ascididemin (II) and eilatin and their biological evaluation shows potent antitrypanosomal activity.
Abstract Mass-directed isolation of the CH 2 Cl 2 /MeOH extract from the Australian marine sponge Ancorina sp. resulted in the purification of a new antimalarial β-carboline, (+)-7-bromotrypargine 1… (More)
Chemical investigations of the Australian marine sponge Ecionemia geodides resulted in the isolation of two new pyridoacridine alkaloids, ecionines A (1) and B (2), along with the previously isolated… (More)