Roger Schecter

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Many in vitro tumor models have been examined to help understand the precise mechanisms responsible for drug resistance. The importance of these results in vivo remains uncertain. MatB 13762 is a rat mammary adenocarcinoma cell line that can be grown both in vitro and as a solid tumor in Fischer 344 rats, thus permitting the examination of tumor cell drug(More)
The objective of this study was to investigate the impact of rivastigmine therapy on attention, apathy, anxiety and agitation in patients with mild-to-moderate Alzheimer's disease (AD) in a real-world clinical setting. Patients with mild-to-moderate AD were enrolled in the study by physicians across Canada. They were treated with open-label rivastigmine(More)
We previously reported the production of a panel of murine monoclonal antibodies which recognize glycoproteins abnormally expressed in human breast tumours. Using two of these antibodies, a double antibody radioimmunoassay was designed to quantify levels of these breast tumour marker glycoproteins in serum. Marker levels greater than 28 units were(More)
A major limitation to successful cancer treatment is the existence of drug resistance. While several mechanisms of drug resistance have now been well characterized, mechanisms of resistance to alkylating drugs have remained less well defined. Several experimental models of alkylator resistance have implicated isoforms of glutathione S-transferase (GST) but(More)
An initial investment procedures were implemented. The waste reduction for Maola was predicted to be 300,000 lb BOD5/yr when these changes are implemented. for the changes was estimated at $54,000. Annual increased costs were estimated to total $35,000. With implementation and the above investment it is estimated that the net savings per year could total as(More)
Objectives: To identify current practices and care gaps for elderly patients admitted following a hip fracture, and to characterize patients' patterns of functional recovery over 1-year. Relevance Increased awareness of existing gaps and improving our understanding of patients' recovery can help optimize patients' outcomes. Methods: Forty community-dwelling(More)
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