S Michal Jazwinski1
Michael V Miceli1
Paul A Kirchman1
James C Jiang1
Sangkyu Kim1
1S Michal Jazwinski
1Michael V Miceli
1Paul A Kirchman
1James C Jiang
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The yeast Saccharomyces cerevisiae has a finite replicative life span. Yeasts possess two prohibitins, Phb1p and Phb2p, in similarity to mammalian cells. These proteins are located in the inner mitochondrial membrane, where they are involved in the processing of newly-synthesized membrane proteins. We demonstrate that the elimination of one or both of the(More)
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