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AIM A world-wide recognised and accepted definition and classification of gastroesophageal reflux disease (GERD) would be highly desirable for research and clinical practice. The purpose of this project was to develop such a generally accepted definition and classification that could be used equally by patients, physicians, and supervisory bodies. METHODS(More)
To systematically review the worldwide evidence on the prevalence of domestic violence against women, to evaluate the quality of studies, and to account for variation in prevalence between studies, using consistent definitions and explicit, rigorous methods. Systematic review of prevalence studies on domestic violence against women. Literature searches of 6(More)
OBJECTIVES Brief, reliable, and valid self-administered questionnaires could facilitate the diagnosis of gastroesophageal reflux disease in primary care. We report the development and validation of such an instrument. METHODS Content validity was informed by literature review, expert opinion, and cognitive interviewing of 50 patients resulting in a(More)
33 Uncertainties Note This paper contains recommendations to writing teams of the IPCC Third Assessment Report on how to improve consistency of assessment and reporting of key uncertainties. Part I (Introduction) provides background information, including the rationale for this guidance. Part II lists the specific recommended steps—concisely in Box 1, and(More)
BACKGROUND Accurate diagnosis and effective management of gastro-oesophageal reflux disease (GERD) can be challenging for clinicians and other health care professionals. AIM To develop a patient-centred, self-assessment questionnaire to assist health care professionals in the diagnosis and effective management of patients with GERD. METHODS Questions(More)
OBJECTIVE To evaluate the association between alarm symptoms and the subsequent diagnosis of cancer in a large population based study in primary care. DESIGN Cohort study. SETTING UK General Practice Research Database. Patients 762 325 patients aged 15 years and older, registered with 128 general practices between 1994 and 2000. First occurrences of(More)
OBJECTIVE To assess the effect of ethnicity on student performance in stations assessing communication skills within an objective structured clinical examination. DESIGN Quantitative and qualitative study. SETTING A final UK clinical examination consisting of a two day objective structured clinical examination with 22 stations. PARTICIPANTS 82(More)
OBJECTIVE To determine the prevalence of symptoms compatible with a clinical diagnosis of irritable bowel syndrome in the general population. DESIGN Validated postal questionnaire sent to 2280 subjects randomly selected in 10 year age bands from the lists of eight general practitioners. The Manning criteria were used to define irritable bowel syndrome. (More)