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OBJECTIVES To estimate familial aggregation and the heritability of total cholesterol (TC), low density lipoprotein-cholesterol (LDL-C) and high density lipoprotein-cholesterol (HDL-C) in families assisted by the Family Doctor Program in a Brazilian city, and to evaluate associations between some environmental factors and familial aggregation of these(More)
Recent evidence indicates that hypoxia enhances the generation of oxidants. Little is known about the role of free radicals in contractility of the rat diaphragm during hypoxia. We hypothesized that antioxidants improve contractility of the hypoxic rat diaphragm and that xanthine oxidase (XO) is an important source of free radicals in the hypoxic diaphragm.(More)
RESUMO Um problema mal formulado origina paradoxos. Uma vez formulado, convenientemente, estes paradoxos sáo fácilmente eliminados. Em mecânica, um dos conceitos geralmente considerado fundamental é o da reversibilidade das suas equações. Desta consideração deriva a bem conhecida afirmaçâo de que a mecânica é irreconciliável com a termodinâmica. Propomo-nos(More)
The diagnosis severe combined immunodeficiency was made in a male infant at the age of 18 wk. Known causes of severe combined immunodeficiency were excluded. The activity of total 5'-nucleotidase (E.C. 3.1.3.5) in the PBMC was found to be strongly decreased. Analysis of the peripheral blood revealed a lymphocytosis, mainly of CD8+ T cells. These lymphocytes(More)
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