Rodrigo C. S. Costa

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Two patients with myocardial bridging of the left anterior descending coronary artery associated with myocardial infarction are described. One of them died from acute cerebral emboli related to cardiac thrombosis in a left ventricular aneurysm. The other died suddenly while sleeping. Both patients were found to have a very long myocardial bridging of the(More)
STUDY OBJECTIVE The objective was to quantify cis and trans fatty acids in maternal plasma and infant cord plasma from adolescent mothers. DESIGN From 80 adolescent healthy mothers, we sampled postpartum maternal blood and umbilical cord blood at birth. Trans fatty acids (tFAs), linoleic (18:2), and arachidonic (AA, 20:4) acids of the n-6 family, and(More)
A 38-year-old Caucasian man collapsed while playing tennis. There was no previous history of cardiac disease. At autopsy, myocardial bridging of the left anterior descending coronary artery was found without any other disease. Whether an isolated myocardial bridge may lead to a fatal cardiac event is a matter to be clarified.
Five new piperidine alkaloids were designed from natural (-)-3-O-acetyl-spectaline and (-)-spectaline that were obtained from the flowers of Senna spectabilis (sin. Cassia spectabilis, Leguminosae). Two semi-synthetic analogues (7 and 9) inhibited rat brain acetylcholinesterase, showing IC50 of 7.32 and 15.1 microM, and were 21 and 9.5 times less potent(More)
This paper presents an algorithm for spots detection in Synthetic Aperture Radar (SAR) images that can be used to support environmental remote monitoring. Monitoring areas with high frequency of oil spillage by accidental or illegal oil discharges can prevent marine damage spreading. But the presence of speckle noise in SAR images limits the visual(More)
LASSBio-767 [(-)-3-O-acetyl-spectaline] and LASSBio-822 [(-)-3-O-tert-Boc-spectaline] were recently described as cholinesterase inhibitors derived from the natural piperidine alkaloid (-)-spectaline, obtained from the flowers of Senna spectabilis (Fabaceae). We investigated their mechanism of inhibition of acetylcholinesterase and their efficacy in(More)
There is evidence in the literature that death following a bee or wasp sting may result from cardiac involvement. This study describes acute cardiac lesions experimentally induced in Wistar Rats submitted to intravenous inoculation of Africanized bee venom (ABV) and killed 1, 4, and 24 h after inoculation. Significant increases in serum enzyme levels were(More)