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CONTEXT AND OBJECTIVE Hemochromatosis is a common inherited disorder of iron metabolism and one of the most important causes of iron overload. The objective was to analyze the presence of C282Y, H63D(More)
Rare HFE variants have been shown to be associated with hereditary hemochromatosis (HH), an iron overload disease. The low frequency of the HFE p.C282Y mutation in HH-affected Brazilian patients may(More)
Sickle cell anemia (SCA), a disorder characterized by both acute and chronic inflammation, exhibits substantial phenotypic variability. Interleukin-1 beta (IL-1β) and IL-6 are important in acute and(More)
OBJECTIVE To evaluate prospectively RBC indices as a diagnostic tool at a high complexity general hospital. METHODS We analyzed 2278 blood cell counts from the core laboratory of our service and we(More)