Rodolfo Cheli

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The histological patterns of the gastric mucosa obtained by endoscopic biopsy were evaluated in two different ethnic groups, each containing one hundred patients without gastro-intestinal diseases. The incidence of atrophic gastritis and intestinal metaplasia increased with age in both groups, revealing a statistically significant difference above 60 years.(More)
The histological pattern of fundic and antral mucosa was evaluated in endoscopically bioptic material obtained from 32 dyspeptic patients in the absence of circumscribed lesions of the stomach, duodenum, hepato-biliary area and pancreas, and in 30 asymptomatic controls. The data obtained failed to reveal any significant differences between the dyspeptic(More)
The therapeutic efficacy of ranitidine, pirenzepine, cimetidine and placebo in the 28 day treatment of duodenal ulcer was evaluated through an open randomized study performed in 120 patients. At the end of treatment, ranitidine, pirenzepine and cimetidine demonstrated a significantly higher efficacy on ulcer healing as well as on symptom relief in(More)
Abnormalities in gastrointestinal motility have been reported in a substantial proportion of patients with functional dyspepsia, supporting the use of prokinetic drugs for treatment of dyspeptic symptoms. To evaluate efficacy and safety of levosulpiride in short-term treatment, 1298 patients were enrolled in a double-blind multicentric study carried out in(More)
The histological and histochemical patterns of fundic and antral mucosa were assessed in 36 patients with normal pyloric competence and in 28 patients with duodenogastric reflux (DGR), evidenced by Capper's test. There was a significant increase of antral gastritis with normal fundic mucosa in patients with DGR compared with controls. In contrast, patients(More)
The authors studied the count and identification of inflammatory cells in biopsies of chronic non specific duodenitis. In superficial and atrophic duodenitis there is an increase of lymphocytes in the epithelial layer and a rich population of plasmacells in the lamina propria. In interstitial duodenitis the intraepithelial lymphocytes are increased; in the(More)
A double-blind, double-dummy, randomized Italian multicenter trial was carried out to compare the efficacy and safety of omeprazole 20 mg in the morning and ranitidine 150 mg b.i.d. in short-term treatment of acute duodenal ulcer. One hundred and twenty-one patients (61 in the omeprazole and 60 in the ranitidine group) with endoscopically proven active(More)