Rodolfo A Trujillo

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Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia. To be eligible for participation, study subjects(More)
BACKGROUND Syphilis is caused by the spirochetal pathogen Treponema pallidum. The local and systemic cellular immune responses elicited by the bacterium have not been well studied in humans. METHODS We used multiparameter flow cytometry to characterize leukocyte immunophenotypes in skin and peripheral blood from 23 patients with secondary syphilis and 5(More)
Ivermectin is the only one of the avermectins that has been widely used in humans, since it is recommended as the treatment of choice for onchocerciasis, a filariasis that produces "river blindness," a parasitic endemic infestation in countries of West Equatorial Africa and in some areas of Central and South America. Also, ivermectin has been used for(More)
BACKGROUND In some settings, the response to pentavalent antimonial therapy for leishmaniasis may be lower in children than in adults. We hypothesized that there are age-dependent pharmacokinetic differences of potential clinical relevance. METHODS We compared the pharmacokinetics of antimony (Sb) in adults and 2 groups of children 3-6 years old who had(More)
BACKGROUND Morphea and lichen sclerosus et atrophicus (LSA) are sclerotic skin lesions of unknown etiology involving connective tissue. The hypothesis of a borrelial origin of morphea and LSA is currently controversial. METHODS Immunoglobulin G (IgG) immunoblot serologies against Borrelia burgdorferi in patients with morphea and LSA were analyzed and(More)
BACKGROUND The etiology of idiopathic guttate hypomelanosis (IGH) remains uncertain; however, solar exposure and heredity have been proposed as causative factors. OBJECTIVE To explore the genetic predisposition to the development of IGH. METHODS A comparative case-control study was performed at a dermatology department at a university hospital.(More)
Authors present a case of carnitine systemic deficiency. Relevant signs being severe muscular hypotonia, fat infiltration of the liver and muscles, as well as frequent episodes of severe hypoglycemia. Infrequent occurrence of this syndrome (this being the first case in our country) and therapeutic implications involved, justify this comment. Evolution is(More)
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