Rocío Santillán Rodríguez

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BACKGROUND Studies of gene expression in experimental cerebral ischaemia models can contribute to understanding the pathophysiology of brain ischaemia and to identifying prognostic markers and potential therapeutic targets. The normalization of relative qRT-PCR data using a suitable reference gene is a crucial prerequisite for obtaining reliable(More)
The paper presents a measurement framework for assessing the e-Governance maturity level of countries through the analysis of municipal websites. The paper also introduces the results of a survey carried out to apply and validate the framework. Applied to municipal websites of different countries, the framework considers websites content and design. For(More)
Hemorrhagic transformation (HT) of cerebral infarction is a common and serious occurrence following acute ischemic stroke. The expression of survivin, a member of the inhibitor of apoptosis protein family, has been shown to increase after cerebral ischemia. This protein has been mainly located at the microvasculature within the infarcted and peri-infarcted(More)
Brain plasticity provides a mechanism to compensate for lesions produced as a result of stroke. The present study aims to identify new transcription factors (TFs) following focal cerebral ischaemia in rat as potential therapeutic targets. A transient focal cerebral ischaemia model was used for TF-binding activity and TF–TF interaction profile analysis. A(More)
This article presents an approach to solve the typing problem using algorithms for set covering. Two algorithms to solve this problem were designed and compared. The typing problem consists of distinguishing all sequences using the least possible reagents. For each reagent, their capacity to distinguish between pairs of sequences is represented in a matrix(More)
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