Rocío Cabrera Lozoya

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Patient-specific cardiac modeling can help in understanding pathophysiology and therapy planning. However it requires to combine functional and anatomical data in order to build accurate models and to personalize the model geometry, kinematics, electrophysiology and mechanics. Personalizing the electromechanical coupling from medical images is a challenging(More)
Cardiac arrhythmias are heart rhythm disruptions which can lead to sudden cardiac death. They require a deeper understanding for appropriate treatment planning. In this thesis, we integrate personalized structural and functional data into a 3D tetrahedral mesh of the biventricular myocardium. Next, the Mitchell-Schaeffer (MS) simplified biophysical model is(More)
Background Most ventricular tachycardias occur on structurally diseased hearts with fibrotic scar, where bundles of surviving tissue promote electrical circuit re-entry. These bundles can be identified on invasive electrophysiological (EP) mapping as local abnormal ventricular activities (LAVA) during sinus rhythm. Although the elimination of LAVAs by(More)
Ventricular radio-frequency ablation (RFA) can have a critical impact on preventing sudden cardiac arrest but is challenging due to a highly complex arrhythmogenic substrate. This work aims to identify local image characteristics capable of predicting the presence of local abnormal ventricular activities (LAVA). This can allow, pre-operatively and(More)
GOAL In this paper, we used in silico patient-specific models constructed from three-dimensional delayed-enhanced magnetic resonance imaging (DE-MRI) to simulate intracardiac electrograms (EGM). These included electrically abnormal EGM as these are potential radiofrequency ablation (RFA) targets. METHODS We generated signals with distinguishable(More)
Current indications for aortic surgery are solely based on maximum aortic diameter and have proven to be nonreliable. There is an urgent need of pertinent information to aid physicians assess surgical risk-benefits and develop an adequate treatment for the patient as the morbidity and mortality risks for these interventions are considerably high. In this(More)
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