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The effects of NGF, BDNF, NT-3, BDNF plus NT-3 and LIF on substance P (SP) mRNA levels were analysed in axotomized dorsal root ganglia (DRGs) in vivo by quantitative in situ hybridization. The growth factors were applied on to the transected sciatic nerve. SP mRNA levels were decreased significantly 3 days after axotomy. NGF (1 microgram) fully counteracted(More)
Autism Spectrum Disorder is a widespread disorder that affects many children across the world. Children affected by autism tend to exhibit an impaired ability to understand non-verbal social cues and actions. Through the use of Applied Behavioral Analysis (ABA) therapy, improvements in behavior and social outcomes have been observed. We have developed a(More)
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