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  • Hui-Chen Hsu, Pingar Yang, +15 authors John D Mountz
  • Biology, Medicine
  • Nature Immunology
  • 2008 (First Published: 1 February 2008)
  • Interleukin 17 (IL-17) is a cytokine associated with inflammation, autoimmunity and defense against some bacteria. Here we show that IL-17 can promote autoimmune disease through a mechanism distinctContinue Reading
  • Robin G. Lorenz, David D. Chaplin, Keely G McDonald, Jacquelyn S. McDonough, Rodney D. Newberry
  • Biology, Medicine
  • Journal of immunology
  • 2003 (First Published: 1 June 2003)
  • The gastrointestinal mucosa contains a complex network of lymphoid compartments that have evolved to efficiently protect the host from invading pathogens. Recently, an additional lymphoid structureContinue Reading
  • Charles O Elson, Yingzi Cong, Vance J. McCracken, Reed A. Dimmitt, Robin G. Lorenz, Casey T Weaver
  • Biology, Medicine
  • Immunological reviews
  • 2005 (First Published: 1 August 2005)
  • There are now many experimental models of inflammatory bowel disease (IBD), most of which are due to induced mutations in mice that result in an impaired homeostasis with the intestinal microbiota.Continue Reading
  • Joel D Schilling, Steven M. Martin, Chia S. Hung, Robin G. Lorenz, Scott J. Hultgren
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2003 (First Published: 1 April 2003)
  • Innate host defenses at mucosal surfaces are critical in the early stages of many bacterial infections. In addition to cells of the traditional innate immune system, epithelial cells can also produceContinue Reading
  • Joel D Schilling, Steven M. Martin, +5 authors Scott J. Hultgren
  • Medicine, Biology
  • Infection and immunity
  • 2003 (First Published: 1 March 2003)
  • The gram-negative bacterium Escherichia coli is the leading cause of urinary tract infection. The interaction between type 1 piliated E. coli and bladder epithelial cells leads to the rapidContinue Reading
  • Joel D Schilling, Matthew A. Mulvey, Carr D. Vincent, Robin G. Lorenz, Scott J. Hultgren
  • Biology, Medicine
  • Journal of immunology
  • 2001 (First Published: 15 January 2001)
  • One mechanism of initiating innate host defenses against uropathogenic Escherichia coli (UPEC) is the production of cytokines by bladder epithelial cells; however, the means by which these cellsContinue Reading
  • Rodney D. Newberry, Robin G. Lorenz
  • Biology, Medicine
  • Immunological reviews
  • 2005 (First Published: 1 August 2005)
  • Gastrointestinal associated lymphoid tissue can be divided into loosely organized effector sites, which include the lamina propria and intraepithelial lymphocytes, and more organized structures, suchContinue Reading