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  • Kirsten E. Lyke, Robin Burges, +8 authors Marcelo B. Sztein
  • Biology, Medicine
  • Infection and immunity
  • 2004 (First Published: 1 October 2004)
  • Inflammatory cytokines play an important role in human immune responses to malarial disease. However, the role of these mediators in disease pathogenesis, and the relationship between host protectionContinue Reading
  • Kirsten E. Lyke, Robin Burges, +8 authors Marcelo B. Sztein
  • Biology, Medicine
  • Infection and immunity
  • 2005 (First Published: 1 September 2005)
  • Understanding HLA-restricted adaptive host immunity to defined epitopes of malarial antigens may be required for the development of successful malaria vaccines. Fourteen epitopes of preerythrocyticContinue Reading
  • Rhys M. G. Stevens, Dirk Petersen, +6 authors Philippa Hanson
  • Medicine
  • 2017 (First Published: 1 June 2017)
  • Background Osteoarthritis causes joint pain, stiffness, and reduced function, leading to disability. CNTX-4975, a highly purified, synthetic trans-capsaicin, targets the transient receptor potentialContinue Reading
  • Randall M. Stevens, John F. Ervin, +5 authors James N. Campbell
  • Medicine
  • Arthritis & rheumatology
  • 2019 (First Published: 1 September 2019)
  • OBJECTIVE The TRIUMPH study assessed the efficacy and safety of high-purity synthetic trans-capsaicin (CNTX-4975) in subjects with chronic osteoarthritis-associated moderate to severe knee pain. Continue Reading