Roberto del Sordo

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The 3β-hydroxysterol Δ14-reductase, encoded by the Tm7sf2 gene, is an enzyme involved in cholesterol biosynthesis. Cholesterol and its derivatives control epidermal barrier integrity and are protective against environmental insults. To determine the role of the gene in skin cholesterol homeostasis, we applied 12-o-tetradecanoylphorbol-13-acetate (TPA) to(More)
The widespread use of BPMN to describe business processes is highlighting the need to integrate the description of the operational flow with domain specific information. In most cases the domain knowledge is already represented in domain ontologies or can be derived from the existing documentation. To preserve the simplicity of the original BPMN model(More)
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