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  • gisele Zapata-sudo, Margarete Manhães Trachez, Roberto T Sudo, Thomas Everett Nelson
  • Medicine
  • Anesthesia and analgesia
  • 2001 (First Published: 1 February 2001)
  • Cardiac toxicity can occur after accidental intravascular injection of bupivacaine. Racemic bupivacaine can inhibit both cardiac Na(+) and Ca(2+) channels, but the contribution of these actions toContinue Reading
  • Thomas Everett Nelson, Marina R. Lin, gisele Zapata-sudo, Roberto T Sudo
  • Medicine
  • Anesthesiology
  • 1996 (First Published: 1 June 1996)
  • BACKGROUND Dantrolene sodium (DS) is a direct-acting skeletal muscle relaxant whose only known action is to block calcium release from intracellular storage sites. The exact site of action for DS isContinue Reading
  • Sharon Schilling Landgraf, Mira Wengert, +5 authors Celso Caruso-Neves
  • Chemistry, Medicine
  • American journal of physiology. Renal physiology
  • 2011 (First Published: 1 February 2011)
  • The renal renin-angiotensin system plays a central role in the development of hypertension. The aim of this work was to verify the expression of angiotensin II receptors AT(1)R and AT(2)R in theContinue Reading
  • C. M. Leal, Sharlene Lopes Pereira, +7 authors gisele Zapata-sudo
  • Chemistry, Medicine
  • European journal of medicinal chemistry
  • 2012 (First Published: 1 September 2012)
  • Several N-acylhydrazone derivatives synthesized from safrole have been found to promote intense vasodilation and antihypertensive activity. The present work describes the synthesis andContinue Reading
  • Sharlene Lopes Pereira, André Mesquita Marques, Roberto T Sudo, Maria Auxiliadora Coelho Kaplan, Gisele Zapata-Sudo
  • Chemistry, Medicine
  • Molecules
  • 2013 (First Published: 7 March 2013)
  • The essential oil of Pectis brevipedunculata (EOPB), a Brazilian ornamental aromatic grass, is characterized by its high content of citral (81.9%: neral 32.7% and geranial 49.2%), limonene (4.7%) andContinue Reading
  • Vera Lucia Adas Pettersen, gisele Zapata-sudo, Juliana Montani Raimundo, Margarete Manhães Trachez, Roberto T Sudo
  • Medicine
  • Anesthesia and analgesia
  • 2009 (First Published: 1 October 2009)
  • BACKGROUND Antidepressant drugs act as potent inhibitors of norepinephrine and/or serotonin reuptake and are widely used with opioids for the treatment of chronic pain. The mechanism of thisContinue Reading
  • Eugênio P Queiroz-Madeira, Lucienne da Silva Lara, +8 authors Celso Caruso-Neves
  • Chemistry, Medicine
  • Biochimica et biophysica acta
  • 2010 (First Published: 1 March 2010)
  • Clinical and experimental data show an increase in sodium reabsorption on the proximal tubule (PT) in essential hypertension. It is well known that there is a link between essential hypertension andContinue Reading