Roberto N. De Guzman

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Hantaviruses, of the family Bunyaviridae, are present throughout the world and cause a variety of infections ranging from the asymptomatic to mild and severe hemorrhagic fevers. Hantaviruses are enveloped anti-sense RNA viruses that contain three genomic segments that encode for a nucleocapsid protein, two membrane glycoproteins (Gn and Gc), and an RNA(More)
Matrix metalloproteinases (MMPs) are important enzymes for extracellular matrix degradation. Cleavage of collagen by MMP-8 is an important regulator of tissue remodeling in wound healing and repair, but it also contributes to the exacerbation of several inflammatory diseases and can serve a protective role in early stages of cancer. In addition through its(More)
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