Roberto Mantovan

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AIMS This multicentre, randomized trial compared three strategies of AF ablation: ablation of complex fractionated electrograms (CFE) alone, pulmonary vein isolation (PVI) alone, and combined PVI + CFE ablation, using standardized automated mapping software. METHODS AND RESULTS Patients with drug-refractory, high-burden paroxysmal (episodes >6 h, >4 in 6(More)
OBJECTIVES To evaluate the time to onset and the predictors of atrial fibrillation (AF) during long term follow up of patients with typical atrial flutter (AFL) treated with transisthmic ablation. DESIGN Prospective multicentre study. METHODS AND RESULTS 383 patients (75.4% men, mean (SD) age 61.7 (11.1) years) who underwent transisthmic ablation for(More)
Delayed gadolinium enhancement magnetic resonance (DE-MR) imaging can be used for in vivo detection of left atrium (LA) fibrosis and scarring, whose identification is important for atrial fibrillation (AF) treatment. This study presents a new tool for 3D visualization of cardiac LA fibrosis based on DE-MR imaging and its qualitative validation by comparison(More)
In atrial fibrillation, electro-anatomical maps (EAM) are used for ablation guidance. Yet, the anatomy reconstructed by the navigation system is known to be poorly accurate. This makes catheter navigation challenging and, as such, might affects ablation's outcome. To ease navigation, existing systems allow co-registering EAMs with pre-operative MR scans by(More)
Radiofrequency catheter ablation (RFA) is an important and promising therapy for a trial fibrillation (AF) patients. About 50% of patients present AF recurrence during the first three months of follow-up. Several studies have been performed to assess the relationship between left atrium (LA) volume and AF recurrence following RFA. In fact, a trial(More)
Atrial fibrillation (AF) is the most common type of arrhythmia and the mechanisms that sustain it are not yet clearly identified. To target AF mechanisms, many theories on atrial electrical activation have been proposed. Since phase distribution of electrogram (EGM) changes over time is less affected by noise than EGM amplitude, phase analysis is one of the(More)
Catheter ablation of atrial fibrillation (AF) is a promising therapy, whose success is limited by uncertainty in the knowledge of the mechanisms sustaining the arrhythmia. Many theories based on atrial electrical activation or on atrial structural remodeling have been proposed to target AF mechanisms. We hypothesized two prospective approaches could be(More)
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