Roberto Mantovan

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AIMS This multicentre, randomized trial compared three strategies of AF ablation: ablation of complex fractionated electrograms (CFE) alone, pulmonary vein isolation (PVI) alone, and combined PVI + CFE ablation, using standardized automated mapping software. METHODS AND RESULTS Patients with drug-refractory, high-burden paroxysmal (episodes >6 h, >4 in 6(More)
Atrial fibrillation (AF) is the most common type of arrhythmia and the mechanisms that sustain it are not yet clearly identified. To target AF mechanisms, many theories on atrial electrical activation have been proposed. Since phase distribution of electrogram (EGM) changes over time is less affected by noise than EGM amplitude, phase analysis is one of the(More)
Catheter ablation of atrial fibrillation (AF) is a promising therapy, whose success is limited by uncertainty in the knowledge of the mechanisms sustaining the arrhythmia. Many theories based on atrial electrical activation or on atrial structural remodeling have been proposed to target AF mechanisms. We hypothesized two prospective approaches could be(More)
Delayed gadolinium enhancement magnetic resonance (DE-MR) imaging can be used for in vivo detection of left atrium (LA) fibrosis and scarring, whose identification is important for atrial fibrillation (AF) treatment. This study presents a new tool for 3D visualization of cardiac LA fibrosis based on DE-MR imaging and its qualitative validation by comparison(More)
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