Roberto Mantovan

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AIMS This multicentre, randomized trial compared three strategies of AF ablation: ablation of complex fractionated electrograms (CFE) alone, pulmonary vein isolation (PVI) alone, and combined PVI + CFE ablation, using standardized automated mapping software. METHODS AND RESULTS Patients with drug-refractory, high-burden paroxysmal (episodes >6 h, >4 in 6(More)
BACKGROUND Early recurrences of atrial tachyarrhythmias (ERAT) are common after atrial fibrillation (AF) ablation, and predict late recurrences (LR). We sought to determine the impact of different ablation strategies on ERAT and LR. METHODS AND RESULTS The STAR-AF trial randomized 100 patients with paroxysmal or persistent AF to ablation of complex(More)
Catheter ablation of atrial fibrillation (AF) is a promising therapy, whose success is limited by uncertainty in the knowledge of the mechanisms sustaining the arrhythmia. Many theories based on atrial electrical activation or on atrial structural remodeling have been proposed to target AF mechanisms. We hypothesized two prospective approaches could be(More)
Delayed gadolinium enhancement magnetic resonance (DE-MR) imaging can be used for in vivo detection of left atrium (LA) fibrosis and scarring, whose identification is important for atrial fibrillation (AF) treatment. This study presents a new tool for 3D visualization of cardiac LA fibrosis based on DE-MR imaging and its qualitative validation by comparison(More)
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