Roberto Castronari

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Septic arthritis is a clinical manifestation of group B Streptococcus (GBS) infection in both neonates and adults. Because macrophages are known to participate in tissue injury, the role of this cell population in GBS-induced arthritis was investigated. Mice were rendered monocytopenic by administration of etoposide, a drug that selectively depletes the(More)
BACKGROUND Breastfeeding has a major impact on CMV epidemiology. Postnatal CMV reactivation's incidence during lactation is nearby the maternal seroprevalence. Although perinatal CMV infection has practically no consequences in term newborn, it may cause, in some cases, a severe symptomatic disease in preterm newborns. The aims of the present study are to(More)
Reactivation of latent human cytomegalovirus following allogeneic transplantation is a major cause of morbidity and mortality and predisposes to severe complications. Thymosin alpha1 (Talpha1), a naturally occurring thymic peptide, is approved for treatment of some viral infections and as an immune adjuvant. Talpha1 successfully primed dendritic cells (DCs)(More)
Le infezioni da microrganismi del complesso ToRCH (Toxoplasma gondii, virus della rosolia, citomegalovirus, herpes simplex 1 e 2) rappresentano le più importanti cause di patologie fetali e neonatali. Si tratta di microrganismi diversi sia da un punto di vista tassonomico (Toxoplasma gondii è un protozoo, gli altri sono virus) sia da un punto di vista dei(More)
INTRODUCTION In healthy subjects, Cytomegalovirus infection can be asymptomatic or manifest as mononucleosis syndrome, but organ disease has also been reported. However, in immunocompromised patients this infection can lead to its most significant and severe disease and even mortality. When Cytomegalovirus causes a gastrointestinal tract infection, it more(More)
Vaginal trichomoniasis is a sexually transmitted infection caused by Trichomonas vaginalis, a flagellated protozoan. Diagnosis of T. vaginalis infection is mainly performed by wet mount microscopy, with a sensitivity ranging from 38% to 82%, compared to culture, still considered the gold standard. Commercial immunochromatographic tests for(More)
BACKGROUND Mycoplasmas are frequently isolated from the genital tract. New molecular PCR-based methods for the detection of mycoplasmas can better define the real epidemiology of these microorganisms. The aim of this study was to evaluate the prevalence of mycoplasmas in a population of childbearing age women by means of PCR. METHODS This 21-month(More)
In questa rassegna sono stati descritti i principali virus che presentano uno spiccato tropismo per il sistema nervoso centrale (SNC) e sono in grado di produrre patologie sia acute sia croniche. Con l’avanzare delle conoscenze, si amplia sempre di più il pannello di virus considerati neurotropi e, di conseguenza, la necessità di idonei strumenti(More)
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