Roberto Cadeddu

Ezio Carboni2
Dragana Jadzic1
Pietro Paolo Secci1
Riccardo Dore1
Manila Loi1
2Ezio Carboni
1Dragana Jadzic
1Pietro Paolo Secci
1Riccardo Dore
1Manila Loi
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  • Maria Giuseppina Pisu, Riccardo Dore, Maria Cristina Mostallino, Manila Loi, Francesca Pibiri, Roberta Mameli +3 others
  • 2011
Rats deprived of social contact with other rats at a young age experience a form of prolonged stress that leads to long-lasting changes in behavioral profile. Such isolation is thought to be anxiogenic for these normally gregarious animals, and the abnormal reactivity of isolated rats to environmental stimuli is thought to be a product of prolonged stress.(More)
Disulfiram efficacy in treatment of cocaine addiction is attributed to the inhibition of dopamine-β-hydroxylase and reduction in brain noradrenaline (NA)/dopamine (DA) ratio. Using microdialysis, we investigated if disulfiram causes DA release from noradrenergic terminals and modifies cocaine-induced DA release. Disulfiram reduced extracellular NA in the(More)
Since the therapeutic treatment of depression is far from being satisfactory, new therapeutic strategies ought to be pursued. In addition, further investigation on brain areas involved in the action mechanism of antidepressants can shed light on the aetiology of depression. We have previously reported that typical and atypical antidepressants strongly(More)
Antidepressants include a relatively wide spectrum of drugs that increase the synaptic concentration of monoamines, mostly through neurotransmitter reuptake blockade. The bed nucleus of stria teminalis (BNST) is considered a relay station in mediating the activation of stress response but also in the acquisition and expression of emotions. BNST is richly(More)
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